Search on: TISSUE INHIBITOR OF METALLOPROTEINASE-3 
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Descriptor English:   Tissue Inhibitor of Metalloproteinase-3 
Descriptor Spanish:   Inhibidor Tisular de Metaloproteinasa-3 
Descriptor Portuguese:   Inibidor Tecidual de Metaloproteinase-3 
Tree Number:   D12.776.645.875.550
Definition English:   A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PROTEIN causes Sorsby fundus dystrophy. 
Pharmacological Action:   Matrix Metalloproteinase Inhibitors
 
History Note English:   1998; see TISSUE INHIBITOR OF METALLOPROTEINASE-3 (NM) 1992-1997 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33428 
Unique Identifier:   D019717 

Occurrence in VHL:
 

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